Name: Ronald Kam

Theme: Immune response: infection

OPTION LIST

A	B lymphocytes	I	Natural killer cells
B	CD4^+ T lymphocytes	J	Neutrophils
C	CD8^+ T lymphocytes	K
D	Dendritic cells	L
E	Hairy cells	M
F	Macrophages	N
G	Mast cells	O
H	Mucosal epithelial cells	P

For each scenario below, choose the most appropriate answer from the list above. Each option may be used once, more than once or not at all.

1. These cells act by releasing the contents of their cytotoxic granules, and are inhibited by MHC class I.

2. These cells interact with Mycobacterium tuberculosis through Toll-like receptors, and mycobacterial reactivation will occur if the function of these cells is impaired.

3. Virally infected host cells bearing MHC class I molecules are induced by these cells to die by apoptosis.

4. MHC class II molecules are constitutively expressed by these cells. When activated, they mature into plasma cells with extensive endoplasmic reticulum.

5. Often the first cells colonised by HIV, these antigen presenting cells carry the virus in mildly acidic early endosomes and pass the virus on to CD4⁺ T lymphocytes.

6. These cells can be induced by IL-4 or IFN-γ to fuse with each other and form large, multinucleated cells.

ANSWERS

1. I

2. F

3. C

4. A

5. D

6. F